The birth of yet another laboratory mouse is hardly worth noting unless the furry creature is the first to be developed from stem cells that do not involve embryonic cells. That deserves to be called a breakthrough. The new pups, whose creation in two separate labs in China was announced in July, were the first to be bred from induced pluripotent stem (iPS) cells. These are adult cells (usually skin cells) that scientists reprogram back to their embryonic state by introducing four genes. The reprogrammed stem cells are then programmed again to develop into mice, a feat that has been accomplished before only using embryonic stem cells. Breeding an entire mouse that is itself capable of reproducing as the mice did in one of the Chinese labs is a strong sign that iPS cells may be as useful as embryonic stem cells for a potential source of treatments for disease, scientists said.
The Top 10 Everything of 2009
- Top 10 Albums
- Top 10 Animal Stories
- Top 10 Apologies
- Top 10 Art Exhibitions
- Top 10 Awkward Moments
- Top 10 Best Business Deals
- Top 10 Breakups
- Top 10 Buzzwords
- Top 10 Children's Books
- Top 10 Crime Stories
- Top 10 Editorial Cartoons
- Top 10 Facebook Stories
- Top 10 Fashion Faux Pas
- Top 10 Fashion Moments
- Top 10 Feuds
- Top 10 Fiction Books
- Top 10 Fleeting Celebrities
- Top 10 Gadgets
- Top 10 Green Ideas
- Top 10 Heroes
- Top 10 iPhone Apps
- Top 10 Late-Night Jokes
- Top 10 Magazine Covers
- Top 10 Medical Breakthroughs
- Top 10 Movie Performances
- Top 10 Movies
- Top 10 New Species
- Top 10 News Stories
- Top 10 Nonfiction Books
- Top 10 Oddball News Stories
- Top 10 Pariahs
- Top 10 Pictures of the Year
- Top 10 Plays and Musicals
- Top 10 Political Gaffes
- Top 10 Quotes
- Top 10 Religion Stories
- Top 10 Scandals
- Top 10 Scientific Discoveries
- Top 10 Songs
- Top 10 Sports Moments
- Top 10 T-Shirt-Worthy Slogans
- Top 10 TV Ads
- Top 10 TV Episodes
- Top 10 TV Series
- Top 10 Tweets
- Top 10 Underreported Stories
- Top 10 Untruths
- Top 10 Video Games
- Top 10 Viral Videos
- Top 10 Worst Biz Deals
TIME charts the highs and lows of the past year in 50 wide-ranging lists