Fusing boutique-hotel modern with the historic architecture of the Printers Row neighborhood, the Blake's 19th-century Morton Salt building façade leads to an of-the-moment lobby. Its understated interiorthink forties-meets-Zenis decked out with gauzy curtains and low black tables, and the glass-walled business center is perfect for impressing clients. Muted taupe walls in the 162 guest rooms artfully set off the red and maroon bedding and sleek glass desks; many of the quarters are also framed by exceptionally tall windows. Rain showers are de rigueur in the bathrooms, as are porcelain vessel sinks, all part of the hotel's fulfillment of the urban lifestyle fantasy.
Insider Tip: Sample the short ribs or veal carpaccio from the acclaimed Custom House restaurant without changing out of your slippersjust pick up the phone and dial room service.
Room to Book: For airy 12-foot ceilings and oversize windows, book a corner room, for great views.