Twiggy, born Lesley Hornby, was but a teenager when her name became synonymous with the mod look of London in the 1960s. A gamine haircut she got at the age of 16 jump-started her career, and eventually the cut, along with her long eyelashes and skinny limbs, led the Daily Express, an English newspaper, to declare her the "Face of '66." The prediction proved true; within that year, the London native came out with her first line of branded clothes and her first pop single. A Twiggy Barbie was released the following year. And she hasn't slowed down since: her career in music, television, publishing, activism (animal welfare and breast cancer), film and theater — and, of course, modeling — has continued unabated for more than four decades. Each of Twiggy's projects may be impressive on its own, but her influence is in their sum: her fame was a harbinger of the modern-day supermodels, most especially those who went on to have successes beyond modeling.