Leaf of the dull Oregon grape, as sketched by Clark during the party's excursion in the Pacific Northwest, Feb. 12, 1806. Lewis and Clark recorded the differences between the Oregon grape and the dull Oregon grape, two similar evergreens, on that day.
Lewis and Clark braved the unknown waters of the Missouri to chart America's future. As we approach the 200th anniversary of their sojourn, TIME reflects upon their sacrifice and achievement