Metabolic Disorders: Living with Cystic Fibrosis

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year, but he feels it is still only a help, and no final answer. Optimistic claims have also been made for the administration of a synthetic hormone, similar to testosterone, to speed up the C.F. victim's metabolism. But some doctors complain that improvement after the treatment is mainly superficial and usually shortlived. There is the disadvantage that after a brief growth spurt, a child may be permanently stunted because the hormone shuts down the epiphyses (growth ends) of long bones. Beyond such controversy, the most encouraging news about C.F. is that the combined effect of all the treatments has helped a great many patients to live past adolescence into young adult life. What makes Dr. di Sant'-Agnese and fellow workers in the field happiest is that seven young women with C.F. have borne ten children and, as was hopefully predicted from the recessive nature of the responsible gene, all their offspring are normal.

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