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His main vehicle for it, the special medium through which he staked his claims as seer, prophet and bard, was the hand-etched and -printed book. Part of Blake's uniqueness is that you cannot separate his writings from his art. He was probably the first major European artist of whom this was true. Illuminated manuscripts had been done for hundreds of years before his birth, but usually the script was by one person and the decoration by another, while the actual text had originally been composed by a third.
Blake, however, did all these things, with the result that his books, tiny and rare as they are, "illuminated" in a form of color etching that was essentially his invention, possess an astonishing integration of clarity, density and richness of organic detail. They ennoble the very idea of illustration and erase the boundaries that supposedly distinguish it from "art." You cannot imagine separating the text from the design, or the design from the text, and so there has hardly been an English book creator since--not even William Morris, the greatest one to emerge since Blake--who did not feel the duty of homage to him.