Age: 73
Occupation: U.S. Secretary of Defense
Panetta was a longtime Democratic lawmaker before he ran the CIA where he helped get Osama bin Laden and now the Pentagon. He faces tough challenges both at home, where he's in charge of trimming $487 billion from the Pentagon's coffers over the coming decade, and abroad: the U.S. troop pullout from Afghanistan is under way, and he has to make sure it goes smoothly despite increasing "green on blue" killings and the massacre of 17 Afghan civilians in March, allegedly by a U.S. Army staff sergeant.