Age: 36
Occupation: Entertainer
Previous TIME 100 Appearances: 0
Although he's best known for his gig on How I Met Your Mother (and as Dr. Doogie Howser), NPH, as he's sometimes known, has helped propel America's revived interest in musical theater. His starring role on Joss Whedon's Web musical Dr. Horrible's Sing-Along Blog brought him a number of singing-and-dancing roles, including spots hosting the 2009 Tony and Emmy Awards, as well as the opening number for the 2010 Oscars. It may now be impossible to stage an awards show without him.