Age: 55
Occupation: Comedian
Previous TIME 100 Appearances: 0
His wildly successful nine-season sitcom (you remember, that show about nothing) gave us a new vocabulary (anti-Dentite, anyone?), and was the PG precursor to co-creator Larry David's Curb Your Enthusiasm, which staged a Seinfeld reunion last fall. More than a decade after his show's finale, Seinfeld still has the name recognition — though unfortunately, he's brought it back to NBC with the questionable Marriage Ref.