Age: 56
Occupation: TV host and producer
Previous TIME 100 Appearances: 6
Many have tried to copy her success, and many have failed. Twenty-four years into hosting The Oprah Winfrey Show, the queen of daytime is still racking up the broadcasting achievements. Despite her popularity, Winfrey announced that in 2011, her talk show will come to an end. But she isn't going anywhere: the one-woman media empire is rumored to be starting a new show on the Oprah Winfrey Network.