Produced in 1987 by the Partnership for a Drug-Free America, this iconic PSA makes use of everyday household items — namely, an egg and a frying pan — to illustrate how narcotics affect the body. (Fresh egg = your brain; fried egg = your brain on drugs.) The ad, recognized by marketing experts as one of the most influential in history, spawned a number of spoofs as well as a disturbing sequel in 1998 starring actress Rachael Leigh Cook.