AGE: 54
OCCUPATION: CEO of Temasek Holdings, wife of Singapore's Prime Minister
NUMBER OF TIME COVERS: 0
PREVIOUS APPEARANCES ON THE TIME 100: 1
PRO: Ranked the third most important woman in the world by Forbes, the low-profile Ho has proved an adept businesswoman, boosting the portfolio of Singapore's national investment holding company to over $110 billion.
CON: Though she certainly knows finance, she's not invulnerable to mistakes — her disastrous decision to buy the Shin Corporation in 2006 is referenced as often as her many accomplishments.