AGE: 44
OCCUPATION: Actor, producer, phil-activist
NUMBER OF TIME COVERS: 1
PREVIOUS APPEARANCES ON THE TIME 100: 0
PRO: To his credit, he's never let his relationship with Angelina Jolie turn into a circus: he's managed to keep the focus on his charity work in New Orleans and Africa. That said, his spermatozoa do appear to function freakishly well.
CON: The Assassination of Jesse James, arguably his finest work in years, had a limited release and was criminally underwatched. And despite his general dignity, his flashbulb-lit public persona does seem to erode his "seriousness" as an actor.