Toxicology: Low-Calorie Sweeteners

There are so many weight watchers and calorie counters in the U.S. that each year they consume almost 1,500 tons of saccharin and 7,500 tons of cyclamates. The cyclamates come in liquid form or in tablets for use at home, and are dissolved in most low-calorie soft drinks by their makers. Are they safe? For years, the U.S. Food and Drug Administration thought so and recommended no limit on consumers' intake.

Last month, Food and Drug had a slight change of heart. On the strength of a report by a special committee of...

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