The practice of medicine, doctors are fond of saying, is more art than science. Yet it's the guiding hand of science that directs them to reconsider treatments and make new educated guesses when a patient's symptoms don't go by the book. That's the force that will continue to reshape the way doctors manage heart disease, cancer and obesity in the coming years.
Every year since 1900, with only one exception (1918, when the influenza epidemic claimed more lives), heart disease has had the dubious honor of being the U.S.'s leading killer. Lowering cholesterol levels, specifically the low-density lipoproteins (LDL) that make...