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How do you pick the 100 most influential men and women of 2005? Some people are obvious, thanks to their position; that is why George W. Bush is once again part of the TIME 100, along with Hu Jintao of China. Some, I think it is fair to say, were not household names a year ago, such as Viktor Yushchenko of Ukraine. Some belong on the list because of how they set the agenda outside their day job (Bill Gates, for his charity work) or make their daytime-TV job into a guide for how to live a meaningful life (Oprah Winfrey)....

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