COVER
How the First Nine Months Shape the Rest of Your Life (Science)
Cancer. Heart disease. Obesity. Depression. The new science of fetal origins traces adult health to our experience in the womb
ESSAY
The Stumbling Blocks to a Big GOP Win (Commentary / In the Arena)
A big GOP year? Perhaps, but a much fiercer battle for primacy inside the Republican Party is already under way
Why $1,700 Means Joel Stein is Rich (The Awesome Column)
With great wealth comes great responsibility. So what should I do with my $1,700 tax-break savings?
NATION
Haley Barbour: GOP Kingmaker or Candidate? (The Well / Profile)
Republican Mississippi Governor Haley Barbour is having a very good 2010. Does that mean he'll be ripe for the presidential contest in 2012?
Should the Highest Court Protect the Ugliest Speech? (The Well / Law)
A religious group pickets soldiers' funerals and taunts their families. Now the Supreme Court will decide if the First Amendment protects this kind of hatemongering
How to Fight a Scourge: Scenes from the Bedbug Summit (The Well / Nation)
The mood was grim in Chicago, as exterminators and scientists from around the country gathered to propose solutions to the nation's bedbug infestation
WORLD
Postcard from New Delhi
The Commonwealth Games were meant to showcase the new greatness of a developing India. But they have become a source of deep anger instead
BRIEFING
The Moment
9|19|10: Gulf of Mexico
The World
10 ESSENTIAL STORIES
How Palin Is like Clinton (Washington: The Politics Page)
Bill Clinton is the best handicapper in American politics. So when, on the eve of his annual Clinton Global Initiative conference in New York City, he assessed the power and peril of Sarah Palin, everybody paid attention
Emanuel Could Leave the White House in October (Washington: The Politics Page)
If White House chief of staff Rahm Emanuel decides to run for Chicago mayor, the decision could come before Election Day
Lab Report: Health, Science and Medicine
Verbatim
Jill Johnston (Milestones)
James Bacon (Milestones)
Milestones (Milestones)
ARTS & ENTERTAINMENT
The Making of the Facebook Movie: A TIME Roundtable (Movies)
David Fincher and Aaron Sorkin sat down with TIME's Lev Grossman to talk about why they made The Social Network, a movie about Facebook
The Facebook Playbook
Who did what to whom, and why. Allegedly
The 15% Solution: Are Jon Stewart and Stephen Colbert Joking? (Tuned In)
Do we really need comedians to take politics back from the lunatics? Apparently, yes
Tom Selleck (Q&A)
The star of Magnum P.I. talks to TIME about his new role on the CBS show Blue Bloods, his mustache, and a Magnum comeback
Short List
TIME'S PICKS FOR THE WEEK
SCIENCE
Code Blue (Environment / Special Report)
One woman's quest to save our oceans the simple way: protect them
The Otherworldy Flora and Fauna of the Coral Triangle
The breathtaking beauty of the reefs that are home to the world's most diverse assortment is under threat
Sylvia Earle
Video: Sylvia Earle, an oceanographer who is nicknamed "Her Deepness", is making her dream of saving oceans a reality
SOCIETY
Pressing Forward: The Future of Your Remote (Life / Techland)
Old-school remotes make way for the TV controls of the future
Shark-Fin Soup and the Conservation Challenge (Life / Going Green)
Shark-fin soup is eaten at weddings and other celebrations across Asia. But this gesture of largesse comes with a big environmental price tag
Strip Search: How Safe are Airports' New X-ray Scanners? (Life / Health)
How safe are airports' new low-radiation scanners?
SPECIAL SECTION
The Secret's Out: Can Swiss Banking Adapt to Scrutiny? (Global Business / Banking)
With privacy laws changing, Swiss banks need to find another competitive advantage. Do they have one?
Wrist Watch (Global Business / Marketing)
There's no evidence that sports bracelets work. And none that the pros and fans buying them care, either
Get Current on Currencies (Global Business / Investment Horizon)
Why the money of other nations is becoming an asset class rather than a commodity
Business Books (Global Business)
The Internet's power to bust paradigms isn't finished. People who ignore it are
PEOPLE
10 Questions for William Shatner (10 Questions)
He stars in CBS's Twitter-inspired sitcom $#*! My Dad Says. William Shatner will now take your questions
ALSO IN THIS ISSUE
Social Media Roundtable (Time 100 Roundtable)
TIME 100 Social Media Roundtable
Video: Four panelists from around the world of social media talk with editor Rick Stengel about how to make the world safe for democracy, using the Internet