Previous TIME 100 Appearances: 0
Her best-selling reminiscence of Texas girlhood, The Liars' Club (1995), kicked off the memoir boom, and the acidly funny Karr is still its queen. The latest chapter in the story of her life, Lit, was published in 2009 and was one of TIME's best nonfiction books of the year. James Frey has nothing on her.
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