Occupation: Comedian, actress
Previous TIME 100 Appearances: 0
It's not often that a late-night host and comedian changes gears to play a thoroughly unsympathetic, abusive mother in an indie film and then racks up every possible honor for it, from the National Board of Review to the Golden Globes to the Oscars. Mo'Nique's Academy Award for Best Supporting Actress for her role in Precious makes her one to watch, this year and beyond.
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