Baby, It's You! And You, And You...

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And it helps explain why so much of the research is being done secretly. We may learn of the first human clone only months, even years, after he or she is born--if the event hasn't happened already, as some scientists speculate. The team that cloned Dolly waited until she was seven months old to announce her existence. Creating her took 277 tries, and right up until her birth, scientists around the world were saying that cloning a mammal from an adult cell was impossible. "There's a significant gap between what scientists are willing to talk about in public and their private aspirations," says British futurist Patrick Dixon. "The law of genetics is that the work is always significantly further ahead than the news. In the digital world, everything is hyped because there are no moral issues--there is just media excitement. Gene technology creates so many ethical issues that scientists are scared stiff of a public reaction if the end results of their research are known."

Of course, attitudes often change over time. In-vitro fertilization was effectively illegal in many states 20 years ago, and the idea of transplanting a heart was once considered horrifying. Public opinion on cloning will evolve just as it did on these issues, advocates predict. But in the meantime, the crusaders are mostly driven underground. Princeton biologist Lee Silver says fertility specialists have told him that they have no problem with cloning and would be happy to provide it as a service to their clients who could afford it. But these same specialists would never tell inquiring reporters that, Silver says--it's too hot a topic right now. "I think what's happened is that all the mainstream doctors have taken a hands-off approach because of this huge public outcry. But I think what they are hoping is that some fringe group will pioneer it and that it will slowly come into the mainstream and then they will be able to provide it to their patients."

All it will take, some predict, is that first snapshot. "Once you have a picture of a normal baby with 10 fingers and 10 toes, that changes everything," says San Mateo, Calif., attorney and cloning advocate Mark Eibert, who gets inquiries from infertile couples every day. "Once they put a child in front of the cameras, they've won." On the other hand, notes Gregory Pence, a professor of philosophy at the University of Alabama at Birmingham and author of Who's Afraid of Human Cloning?, "if the first baby is defective, cloning will be banned for the next 100 years."

"I wouldn't mind being the first person cloned if it were free. I don't mind being a guinea pig," says Doug Dorner, 35. He and his wife Nancy both work in health care. "We're not afraid of technology," he says. Dorner has known since he was 16 that he would never be able to have children the old-fashioned way. A battle with lymphoma left him sterile, so when he and Nancy started thinking of having children, he began following the scientific developments in cloning more closely. The more he read, the more excited he got. "Technology saved my life when I was 16," he says, but at the cost of his fertility. "I think technology should help me have a kid. That's a fair trade."

Talk to the Dorners, and you get a glimpse of choices that most parents can scarcely imagine having to make. Which parent, for instance, would they want to clone? Nancy feels she would be bonded to the child just from carrying him, so why not let the child have Doug's genetic material? Does it bother her to know she would, in effect, be raising her husband as a little boy? "It wouldn't be that different. He already acts like a five-year-old sometimes," she says with a laugh.

How do they imagine raising a cloned child, given the knowledge they would have going in? "I'd know exactly what his basic drives were," says Doug. The boy's dreams and aspirations, however, would be his own, Doug insists. "I used to dream of being a fighter pilot," he recalls, a dream lost when he got cancer. While they are at it, why not clone Doug twice? "Hmm. Two of the same kid," Doug ponders. "We'll cross that bridge when we come to it. But I know we'd never clone our clone to have a second child. Once you start copying something, who knows what the next copies will be like?"

In fact the risks involved with cloning mammals are so great that Wilmut, the premier cloner, calls it "criminally irresponsible" for scientists to be experimenting on humans today. Even after four years of practice with animal cloning, the failure rate is still overwhelming: 98% of embryos never implant or die off during gestation or soon after birth. Animals that survive can be nearly twice as big at birth as is normal, or have extra-large organs or heart trouble or poor immune systems. Dolly's "mother" was six years old when she was cloned. That may explain why Dolly's cells show signs of being older than they actually are--scientists joked that she was really a sheep in lamb's clothing. This deviation raises the possibility that beings created by cloning adults will age abnormally fast.

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