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The discovery of a third gene contributing toAlzheimer's Disease"puts scientists on the path to discovering how this deadly disease is formed," says TIME's Alice Park. "Having identified the third gene," says Park, "researchers can now move to a new phase of study to look atwhat causes them to form the plaque on the brainthat contributes to memory loss and other symptoms. Then they can start investigating drugs to combat plaque formation; even further down the road would be gene therapy." Alzheimer's claims about 100,000 Americans annually.