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At a time when any new CIA director is expected to play caretaker while a presidential commission contemplates reforms, Clinton Administrationnominee John Deutch today said he plans major changes from day one. "I would anticipate taking significant action immediately upon confirmation," Deutch, now deputy defense secretary, told the Senate Intelligence Committee as his confirmation hearings began. President Clinton persuaded the reluctant Defense Department officialto take the jobonly after an earlier nominee, retired Air Force Gen. Michael Carns, disclosed a "nanny problem." Deutch told senators he would fill much of upper CIA management with his own people, saying the move would help improve morale in thewake of the Aldrich Ames spy scandal.