Hormone Hazards

Long-term estrogen use may double the risk of ovarian cancer. But look beyond the numbers

I am really looking forward to the year 2005. That's when a large clinical trial called the Women's Health Initiative (WHI) should finally answer the question "Do the benefits of taking estrogen and progestin for years, even decades, after menopause outweigh any risks?" There has been lots of evidence over the years that the answer is yes and yet plenty of data that lean toward no. Just last week a report in the Journal of the American Medical Association said that taking estrogen for 10 years or more doubles a woman's risk of dying from ovarian cancer. Is it any wonder...

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