The Great Pain Debate

A new breed of analgesics is about to battle aspirin and ibuprofen for a place in your medicine cabinet

Chances are you've had plenty of dealings with those irksome little enzymes cyclooxygenase 1 and cyclooxygenase 2, better known as cox-1 and cox-2. They're what you suppress every time you take an aspirin. Trouble is, aspirin, ibuprofen and other over-the-counter pain killers wreak havoc on the stomach lining--and kill thousands every year through internal bleeding. So last week, an FDA advisory panel gave the green light to Celebrex, the first of a new breed of drugs called cox-2 inhibitors that promise to deliver all the relief of today's pain killers with none of the side effects. Celebrex, made by Monsanto's G.D....

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