DNA Therapy

The new, virus-free way to make genetic repairs

For years scientists doing gene therapy have had to rely on viruses to do their heavy lifting. Doctors would put whatever snatches of DNA they wanted to change into the viruses and then infect their patients with millions of them, hoping that some would hit the target. Unfortunately, the DNA patches would rarely land where they were supposed to, and even when they did, they usually fell out within weeks. A permanent genetic fix always seemed maddeningly out of reach.

Until now. Researchers led by Dr. Clifford Steer at the University of Minnesota Medical School report in the current Nature Medicine...

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