MIGHTY MOUSE

MUSCLE-BOUND MUTANTS COULD POINT THE WAY TO BEEFIER COWS AND HUMANS

From the outside, the new strain of mice looked a little, well, lumpy. But when scientists peeled back their fur and skin, what had seemed like extra baggage in the shoulders and hips turned out to be pure muscle--two to three times the muscle mass of the average pip-squeak rodent. These were not your ordinary genetically engineered laboratory mice; these were Mighty Mice.

Dr. Se-Jin Lee and his colleagues at the Johns Hopkins School of Medicine didn't set out to create muscle-bound lab specimens. As reported in last week's Nature, they wanted to find out how a particular protein, a growth...

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