ANATOMY OF MELANCHOLY

SCIENTISTS TAKE A PICTURE OF DEPRESSION AND DISCOVER THAT IT ACTUALLY CHANGES THE SHAPE OF THE BRAIN

The images were so striking that researchers repeated the experiment three times just to make sure they had done it right. But each new set of pictures only confirmed what the previous ones had shown: that one portion of the brain is significantly smaller and less active in people suffering from hereditary depression. "Most of the time the differences we find in the brain are very subtle," says Dr. Wayne Drevets, who led the team of scientists from Washington University in St. Louis, Missouri. "To see something stand out to this degree is remarkable."

It may turn out to be the...

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