How many people struggling mightily to keep their weight in check wouldn't trade places with the mice in Dr. Jeffrey Friedman's laboratory? Two weeks earlier, these roly-poly fur balls weighed three times as much as a mouse should, and they still couldn't stop snacking. After daily injections of a new hormone, however, the tubby rodents suddenly started consuming less food and burning more fat. They shed those excess ounces and trimmed 30% off their bloated size. Even better, their cholesterol readings fell, as did the high glucose levels that made them mildly diabetic. Virtually overnight, it seemed, the mice perked up,...
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