Cold Water on Lorenzo's Oil

Research casts doubt on a Hollywood remedy

The popular movie Lorenzo's Oil did more than tout a possible cure for a rare and fatal hereditary disease. Based on a true story, the 1992 film also vilified the medical establishment for being slow to accept the possibility that a combination of vegetable oils developed by Augusto and Michaela Odone might have improved the condition of their son Lorenzo, 14, who suffers from a degenerative nerve illness called adrenoleukodystrophy. Now a two-year study from France concludes that the remedy, named for the Odones' son, is worthless -- at least for the milder, adult form of the ailment. Writing in the...

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