Colon Cancer: A Lethal Legacy

Scientists have discovered a renegade gene that causes colon cancer

For almost a century, medical researchers have tried to figure out why colon cancer seems to run in certain families. Did their misfortune result from blind chance, a shared exposure to some cancer-causing trigger in the environment or their diet? Or could they have inherited a rogue gene that made them more susceptible to malignancy? Now a team led by scientists from Johns Hopkins University and the University of Helsinki believe that they have found the answer. "What has heretofore been called familial colon cancer can now be called heritable colon cancer," says Dr. Bert Vogelstein, professor of oncology at Johns...

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