Shark Bites Microbe

The denizen of the deep yields a powerful killer of bacteria and fungi

SCIENTISTS HAVE LONG WONDERED WHY SHARKS never seem to get sick. Despite a relatively primitive immune system, they almost never get infected after suffering wounds, and they seem to be cancer-free. Now a team of scientists, working with dogfish taken from the Gulf of Maine, think they may have the answer: a powerful antibiotic found in virtually every cell of the shark's body. The new compound, a chemical cousin of cholesterol, does not belong to any known class of antibiotics, according to a report published by the National Academy of Sciences. But it is surprisingly effective against a broad range of...

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