Aids Triple Play

Researchers hit on a new chemical combination to combat the virus

IT IS NOT A CURE. IT IS NOT EVEN A TREATMENT YET. But preliminary research, revealed in Nature, points to a new way to attack the AIDS virus. By targeting a single phase in the virus' life cycle with three drugs, Yung-Kang Chow and his colleagues at Massachusetts General Hospital found that they could stop the infection cold -- in the test tube anyway.

Operating alone, each of the three drugs -- AZT, ddI and pyridinone -- merely slows down the virus' ability to reproduce. Eventually, the microbe mutates and becomes resistant to treatment. Chow's triple combo, however, appears to overwhelm...

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