Waking Up Genes

A flavor enhancer may provide the first treatment for sickle-cell anemia

OCCASIONALLY, GREATNESS EMERGES FROM THE commonplace. Scientists have found that an ordinary food additive may help people who suffer from sickle-cell anemia, the inherited illness that afflicts up to 100,000 black Americans. A preliminary study in the New England Journal of Medicine suggests that butyrate, a widely used flavor enhancer, can overcome the basic cause of the disease. A genetic flaw leads the body to make abnormal hemoglobin, the blood protein that carries essential oxygen.

Six patients with either sickle-cell anemia or thalassemia, a related blood disorder, showed dramatic improvement after receiving butyrate injections for two to three weeks. Apparently the...

Want the full story?

Subscribe Now

Subscribe
Subscribe

Learn more about the benefits of being a TIME subscriber

If you are already a subscriber sign up — registration is free!