Using Cancer to Fight Cancer

A high-profile researcher plans to inject patients with their own genetically altered tumor cells

For people facing terminal cancer, word of a possible new treatment is a beacon of hope. Few scientists have scattered more rays than Dr. Steven Rosenberg, who has conducted a series of tantalizing though as yet inconclusive experiments at the National Cancer Institute. Rosenberg, a surgeon by training, has repeatedly tried to find new ways to rally the immune systems of cancer patients to combat their own disease. Last week he revealed his most radical effort to date: vaccinating injected patients with their own genetically altered tumor cells in what Rosenberg calls an attempt "to immunize the patient against his own...

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