Science: Making Men

The answer lies in Y

What makes a man? Biologists have long known that the answer lies not in what but in Y. To create a male child, a father's sperm must carry a Y chromosome to fertilize a mother's egg, which always bears an X chromosome. But the site of the specific gene on Y that determines maleness has been elusive. Last week, though, scientists in Britain announced in Nature that they have identified a section of DNA that apparently directs the development of the testes, the male reproductive glands. The gene is being called SRY for sex-determining region Y.

Scientists from London's Imperial Cancer...

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