Medicine: Pain-Killer Alert

Taking too much ibuprofen for too long can lead to kidney failure

Millions of Americans swear by ibuprofen for relief from the aches and pains of arthritis, menstrual cramps and other ailments. But like many other pain killers, ibuprofen, sold under such brand names as Advil and Medipren, can sometimes inflict pain. According to a report in the current Annals of Internal Medicine, the medication could cause kidney failure in about 1% of the people who use it.

In a study of twelve women with mild kidney disease, researchers at Johns Hopkins found that above-normal doses of ibuprofen led to kidney failure in three patients. Two of those patients also had adverse reactions...

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