Medicine: Capsules, Mar. 24, 1980

DES DAUGHTERS

Some 2 million pregnant women had taken DES (diethylstilbestrol) to help prevent miscarriage before the Food and Drug Administration alerted physicians to its dangers in 1971. Doctors suspected that the estrogen drug was causing vaginal and cervical cancer in daughters born to those women, and more recently have also implicated it in genital abnormalities and infertility in sons. Now there is more unsettling news for DES daughters. When they reach childbearing age, they appear to be more vulnerable than others to miscarriageĀ—as well as to stillbirth, premature birth and ectopic pregnancy (in which the fetus grows outside the uterus). Dr....

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