Behavior: Of Pot and Rats

Those who advocate the unrestricted use of marijuana like to point out that there is no proof the drug has a lasting or harmful effect. That argument has now been undermined. At a meeting of the American Chemical Society in Washington last week, Biochemists Harris Rosenkrantz and Yugal Luthra reported the first evidence of basic—and dangerous—chemical changes in the brains of animals exposed to marijuana over a long period of time.

In a series of controlled experiments lasting three months, the scientists gave 160 rats a marijuana extract and THC. a synthetic form...

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