Medicine: Capsules, Jan. 22, 1973

>Some drug manufacturers argue that strict tests for safety and effectiveness are unnecessary for over-the-counter medicines. But two Pennsylvania researchers offer a case study to support the argument for such tests. Dr. Karl Rickels and Peter Hesbacher report in the A.M.A. Journal that Compoz, one of the nation's largest-selling nonprescription daytime sedatives, is no more effective than a placebo in relieving "simple nervous tension." The pair base their report on a study of 166 patients with mild to moderate anxiety who were divided into four groups and given Compoz, aspirin, a placebo and...

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