If tubercle bacilli can float through the air and cause disease in people who inhale them, why cannot weakened bacilli be transmitted the same way to achieve mass vaccination? This was the question that Dr. Gardner Middlebrook and colleagues at Denver's research-wise National Jewish Hospital asked themselves. Last week, after years of testing, they gave the National Tuberculosis Association a tentative answer: no reason why not.
Dr. Middlebrook and Dr. Maurice Cohn put more than 1,000 guinea pigs into chambers rigged so that the ventilators blew in BCG—Bacillus of Calmette and Guerin, a strain of weakened microbes used in vaccination against tuberculosis...
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