Medicine: The Methadone Mess

Thousands of heroin addicts have kicked the habit with the help of the synthetic drug methadone. But lately methadone clinics in major U.S. cities have become centers of increasing controversy. Last week critics of the methadone program got some unexpected support. It came from the same doctors who did more than anyone else to create the massive U.S. methadone program, which is currently treating some 80,000 addicts. In a special report to JAMA, Drs. Vincent P. Dole and Marie Nyswander of Rockefeller University acknowledge that the methadone program, however sound in theory, has...

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