Hematology: Controlling Rh Mismatch

Each year, at least 200,000 U.S. men with blood classified as Rh-positive marry women whose blood is Rh-negative. The mismatch poses no threat to the first child, but with the second there is an almost certain chance of miscarriage, stillbirth or brain damage. The only remedy with promise has been a transfusion, replacing the child's entire blood supply in the womb.

Medical researchers have now found a surer and simpler way to protect the second child by inoculating the mother during a crucial three-day period following the birth of her first child. Heretofore, the problem has...

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