When the new TB drug, isoniazid, was first used (TIME, March 3), doctors noticed that some patients seemed to get a tremendous lift: they felt wonderful, out of all proportion to any real improvement in their lung condition. With some, this euphoria was so marked that it was a nuisance. But Dr. Albert E. Krieser saw no reason to expect the same sort of trouble when he began using Pyricidin (a brand of isoniazid) at Anoka State Hospital, Minn. His patients were both tuberculous and mental cases; most of them had shown nothing resembling a spiritual lift in years.
After three weeks,...
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