Menopausal Muddle

The latest (but likely not the last) word on estrogen therapy

Fifty Thousand deaths. That's the toll Yale University researchers attribute to accurate but incomplete news about the dangers of hormone-replacement therapy (HRT) for postmenopausal women. As a result of that news, a subset of women who could have benefited from HRT avoided it, with fatal consequences.

The harms of HRT were widely broadcast in 2002 after the Women's Health Initiative (WHI) found that the combination of estrogen and progestin prescribed to women about 10 years after menopause to protect them from heart disease actually increased their risk of heart problems and breast cancer. In an about-face, doctors and women alike shunned...

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