The End of Chemo?

Smarter cancer drugs with fewer side effects could make the drip history

Chemotherapy has long been one of medicine's potent weapons against cancer, helping cut cancer deaths by about 20% in the U.S. over the past two decades. But cytotoxins, which target fast-growing cancer cells while killing normal cells too, can be just as brutal on the patient, with side effects ranging from nausea to infection to death.

So researchers are making progress with kinder, gentler ways of targeting cancer that could require nothing more than popping pills, and with fewer side effects. Could the end of chemotherapy be near?

"It's a question we are all asking," says Dr. Martin Tallman, chief of...

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