Chez de Niro

He may be best known for his onscreen performances, but offscreen no role better defines Robert De Niro than unofficial mayor of New York City's Tribeca district. By investing in everything from its dining scene (Nobu) to its arts industry (the Tribeca Film Festival), De Niro has helped establish the 'hood as one of Manhattan's hippest. And his latest debut could be his most ambitious yet: the eight-floor, 88-room Greenwich Hotel.

With its industrial-luxe aesthetic, the hotel (www.thegreenwichhotel.com) looks as if it has been there for a century. But it was actually completed earlier this year,...

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