THE BEST SCIENCE OF 1993

1 The Great Gene Hunt. It was an extraordinarily productive year for the genetic engineers racing to unravel the secrets of human DNA. Scientists not only pinpointed genes linked to more than half a dozen major ailments -- including Lou Gehrig's disease, Huntington's disease, colon cancer, hyperactivity and a type of diabetes -- but also sketched out the first rough map of all human chromosomes. Other researchers explored ways to use this information to replace damaged genes. The first beneficiaries of ''gene therapy'' -- two Ohio girls who have an immune-deficiency disease -- made their public debut after three years of...

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