Your Health

Vitamin E was once thought by some to be the cure for nearly everything. Observational studies suggested that moderately high doses (400 International Units, or IUs) could prevent heart disease, cancer and dementia—and make your skin glow, too. But lately scientists, using more rigorous tests, have had trouble substantiating some of those benefits.

Now comes what may be the crowning blow—at least with respect to staving off heart disease. A double-blind, placebo-controlled trial, published in the Journal of the American Medical Association last week, found that taking 400 IUs of vitamin E each day did nothing to...

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