People to Watch In International Business

JOOST HOLTHUIS Drug Courier

The best-designed drug is useless if it can't go where it's needed, say, in the brain or lungs. CEO Holthuis' tiny OctoPlus, based in the Netherlands, has helped biotechs chemically package 25 drugs to reach bodily ZIP codes and, once there, work efficiently. The seven-year-old private company has been profitable from Day One, and this year revenues jumped 25%, to $5 million. Holthuis, 48, has raised $6 million to speed development of microscopic beads that release drugs gradually into the body. Clinical trials are slated for spring.

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