Hormone-replacement therapy (HRT), which for years was offered to postmenopausal women as a remedy for nearly everything that ailed them, from hot flashes to heart disease, took another hit last week. The Journal of the American Medical Association published the outcome of a seven-year follow-up study that doctors hoped would show, despite disappointing results the first time, that long-term hormone replacement does in fact protect women against heart disease. Instead, the study showed the opposite. Not only did HRT fail to reduce the risk of heart attacks and strokes, it significantly increased the incidence of blood clots and gallbladder disease.
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